Author

Suh Yeon Oh

Cornell UniversityORCID 0000-0002-6908-9336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:CRISPR screen· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew G. ClarkiD· 3 shared Jackson ChamperiD· 3 shared Philipp W. MesseriD· 3 shared Chen LiuiD· 2 shared Jingxian LiuiD· 2 shared Riona ReevesiD· 2 shared Anisha LuthraiD· 1 shared Nathan OakesiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenetics

Andrew G. ClarkORCID

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3 papers

Recent·Most cited

Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs

Samuel E. Champer, Suh Yeon Oh, Chen Liu, Zhaoxin Wen, Andrew G. Clark, Philipp W. Messer, Jackson Champer

The paper models CRISPR homing gene drives with multiple gRNAs, finding optimal gRNA numbers and showing their limited standalone effectiveness but value when combined with other strategies.

Science Advances · Mar 4, 2020Peer-reviewedGenetics

Reducing resistance allele formation in CRISPR gene drives

Jackson Champer, Jingxian Liu, Suh Yeon Oh, Riona Reeves, Anisha Luthra, Nathan Oakes, Andrew G. Clark, Philipp W. Messer

This study evaluates strategies to reduce resistance allele formation in CRISPR gene drives, finding that using the nanos promoter, adding a second gRNA, and using an autosomal male germline drive can lower resistance rates.

Proceedings of the National Academy of Sciences · May 7, 2018Peer-reviewedGenetics

Novel CRISPR/Cas9 gene drive constructs in Drosophila reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

Jackson Champer, Riona Reeves, Suh Yeon Oh, Chen Liu, Jingxian Liu, Andrew G. Clark, Philipp W. Messer

PLoS Genetics · Jul 20, 2017Peer-reviewedGenetics