Author

Riona Reeves

Cornell UniversityORCID 0000-0003-0236-4046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew G. ClarkiD· 3 shared Jackson ChamperiD· 3 shared Jingxian LiuiD· 3 shared Philipp W. MesseriD· 3 shared Anisha LuthraiD· 2 shared Chen LiuiD· 2 shared Suh Yeon OhiD· 2 shared Emily YangiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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3 shared papersGenetics

Andrew G. ClarkORCID

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3 papers

Recent·Most cited

GeneticsGeneticsPeer-reviewedMar 27, 2019

Multiple loci of small effect confer wide variability in efficiency and resistance rate of CRISPR gene drive

Jackson Champer, Zhaoxin Wen, Anisha Luthra…·Andrew G. Clark

The paper investigates how natural genetic variation affects resistance to CRISPR gene drives in Drosophila, finding that resistance rates vary widely and are polygenic with small-effect loci.

46 citations

DrosophilaCRISPR screen

𝕏 PostBluesky

GeneticsProceedings of the National Academy of SciencesPeer-reviewedMay 7, 2018

Reducing resistance allele formation in CRISPR gene drives

Jackson Champer, Jingxian Liu, Suh Yeon Oh…·Philipp W. Messer

This study evaluates strategies to reduce resistance allele formation in CRISPR gene drives, finding that using the nanos promoter, adding a second gRNA, and using an autosomal male germline drive can lower resistance rates.

275 citationstop 1%

CRISPR screenexperimental assay

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GeneticsPLoS GeneticsPeer-reviewedJul 20, 2017

Novel CRISPR/Cas9 gene drive constructs in Drosophila reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

Jackson Champer, Riona Reeves, Suh Yeon Oh…·Philipp W. Messer

295 citationstop 1%

Drosophilaexperimental assay

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