Julien Orlans

A user-friendly goniometer-compatible fixed-target platform formacromolecular crystallography at synchrotrons

The paper introduces a 3D-printed fixed-target platform for macromolecular crystallography that simplifies microcrystal handling and data collection at synchrotrons.

Novel polymer fixed-target microfluidic platforms with an ultra-thin moisture barrier for serial macromolecular crystallography

This paper introduces a polymer film technology for serial macromolecular crystallography that provides an efficient hydration barrier and low X-ray background.

Ambient temperature structural studies of Penicillin-binding Protein 2a of Methicillin-Resistant Staphylococcus aureus with XFELs and synchrotrons

This study presents room-temperature structures of PBP2a using SFX to reveal dynamic features and conformational changes relevant to antibiotic resistance.

Combining MicroED and native mass spectrometry for structural discovery of enzyme-biosynthetic inhibitor complexes

This paper combines MicroED and native mass spectrometry to determine structures of enzyme-inhibitor complexes and identify high-affinity ligands from crude samples.

The nucleating agent crystallophore induces instant protein crystallization

This paper demonstrates how the crystallophore TbXo4 accelerates protein crystallization, enabling high-quality crystals for serial crystallography methods.