Dwayne G. Stupack

The paper introduces a framework to analyze pan-cancer co-expression programs by addressing artifacts in existing methods, showing that gene expression patterns differ between cancer types.

This study identifies YY1 phosphorylation as a key mechanism linking non-apoptotic caspase-8 signaling to METRN induction and MASH fibrosis.

This study identifies a FAK isoform, FAK{Delta}e4, regulated by matrix stiffness, which influences cell migration, invasion, and mechanosensing.

This study shows FAK inhibition in ovarian tumors increases macrophage CXCL13 production via omega-3 fatty acids, enhancing B cell infiltration and immunotherapy response.

The paper shows that deleting FAK in endothelial cells of PYK2-null mice activates p53, suppresses tumor growth, and limits metastasis, while FAK inhibition has different effects.