Author

Yuriy M. Usachev

University of IowaORCID 0000-0002-6948-4627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron D. MickleiD· 1 shared Amy LeeiD· 1 shared Andrew F. RussoiD· 1 shared Andrew J. ShepherdiD· 1 shared Annette D. de KloetiD· 1 shared Annette KlompiD· 1 shared Brian KimiD· 1 shared Bryan A. CopitsiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperNeuroscience

Aaron D. MickleORCID

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3 papers

Recent·Most cited

The voltage-gated Cav Ca2+ channel subunit α2δ-4 is required for locomotor behavior and sensorimotor gating in mice

Annette Klomp, Ryotaro Omichi, Yoh-ichiro Iwasa, Richard J. Smith, Yuriy M. Usachev, Andrew F. Russo, Nandakumar S. Narayanan, Amy Lee

This study investigates the role of the 2{delta}-4 subunit of Cav Ca2+ channels in mice, finding behavioral impairments in motor function and sensorimotor gating.

bioRxiv · Jan 17, 2022 · PreprintNeuroscience

Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on glutamate-induced Ca2+ response

Guanghao Liu, Ramasamy Thangavel, Jacob Rysted, Yohan Kim, Meghan B. Francis, Eric Adams, Zhihong Lin, Rebecca J. Taugher, John A. Wemmie, Yuriy M. Usachev, Gloria S. Lee

The study investigates the role of tau and Fyn interaction in glutamate-induced Ca2+ response using a tau/Fyn double knockout mouse, revealing a Fyn-independent effect of tau and MAP2's compensatory role.

Journal of Neuroscience Research · Aug 26, 2019Peer-reviewedNeuroscience

Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain

Andrew J. Shepherd, Aaron D. Mickle, Bryan A. Copits, Páll Karlsson, Suraj Kadunganattil, Judith P. Golden, Satya Murthy Tadinada, Madison R. Mack, Simon Haroutounian, Annette D. de Kloet, Vijay K. Samineni, Manouela V. Valtcheva, Lisa A. McIlvried, Tayler D. Sheahan, Sanjay R. Jain, , Durga Prasanna Mohapatra

This study identifies macrophage AT2R activation as a key driver of neuropathic pain through ROS/NO-mediated TRPA1 activation in sensory neurons.

bioRxiv · Aug 30, 2017 · PreprintNeuroscience