Rahmi Lee

Co-activation of selective nicotinic acetylcholine receptor subtypes is required for neuroprotection against Alzheimers disease

The paper identifies that co-activation of 7- and 4β2-nAChRs in specific hippocampal interneurons is necessary to reverse AD-related hyperexcitability and memory loss.

δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice

This study shows that δ-catenin haploinsufficiency in mice disrupts social behavior and fear learning, and alters glutamatergic synaptic activity.

American ginseng (Panax quinquefolius L.) extracts (G1899) reverse stress-induced behavioral abnormalities in mice

This study shows that American ginseng extract G1899 reverses both acute and chronic stress-induced behavioral abnormalities in mice by reducing glutamatergic activity and corticosterone levels.

Ketamine reverses chronic stress-induced behavioral changes via Ca2+-permeable AMPA receptors in mice

This study shows low-dose ketamine reverses chronic stress-induced behavioral issues in mice by activating Ca2+-permeable AMPA receptors in the hippocampus.

The autism-associated loss of δ-catenin functions disrupts social behaviors

This paper investigates how the G34S mutation in δ-catenin causes loss of function leading to social dysfunction in ASD by altering glutamatergic activity and GSK3β-mediated degradation.