Junb acts downstream of the Il-11/Stat3 signaling axis to limit tissue damage induced fibro-inflammation during regeneration
Julia Ishaque, Eric Bienert, Amrutha Manikandan, Srinivas Allanki, Laia Cañes Esteve, Jochen Poeling, Stefan Guenther (5992991), Didier Y. R. Stainier, Samuel Tobias Sossalla, Arica Beisaw, Sven Reischauer
This study identifies Junb as a regulator of inflammation during regeneration, showing that its loss leads to fibroinflammatory damage and impaired regeneration in zebrafish.
bioRxiv · Aug 9, 2026 · PreprintImmunology