Author

Takafumi Ishida

Fukushima Medical UniversityORCID 0000-0002-0896-3069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Akiomi YoshihisaiD· 2 shared Masayoshi OikawaiD· 2 shared Ryo OgawaraiD· 2 shared Satoshi OkochiiD· 2 shared Shohei Ichimura· 2 shared Shunsuke MiuraiD· 2 shared Tetsuro YokokawaiD· 2 shared Tomofumi MisakaiD· 2 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPathology

Akiomi YoshihisaORCID

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4 papers

Recent·Most cited

An iPSC-based experimental framework for investigating phenotypic variation associated with Jomon ancestry in the present-day Japanese population

Yuka Nakamura, Yusuke Watanabe, Hideyuki Tanabe, Asei Hirai, Koichi Higashi, Ken Kurokawa, Atsushi Toyoda, Tomoaki Kato, Masayoshi Tsukahara, Kae Koganebuchi, Yusuke Hamazaki, Takanori Takebe, Masanori Imamura, Takafumi Ishida, Jun Ohashi, Hiroki Oota

The paper develops a hiPSC-based framework to study ancestry-related phenotypic variation in the Japanese population, finding no hepatic triglyceride differences despite genetic associations.

bioRxiv · Oct 11, 2026 · PreprintGenomics

TGM2-mediated histone serotonylation is an epigenetic cardioprotective mechanism in HFpEF

Ryo Ogawara, Tomofumi Misaka, Yoshinori Suzuki, Satoshi Okochi, Shohei Ichimura, Shunsuke Miura, Tetsuro Yokokawa, Shu Taira, Satoshi Waguri, Masayoshi Oikawa, Akiomi Yoshihisa, Takafumi Ishida, Yasuchika Takeishi

This study identifies TGM2-mediated histone serotonylation as a cardioprotective epigenetic mechanism in HFpEF, showing its role in stress response and cardiac function.

bioRxiv · Jul 1, 2026 · PreprintPathology

Macrophage extracellular traps promote maladaptive cardiac remodelling and heart failure via PAD4-dependent mechanisms

Shohei Ichimura, Tomofumi Misaka, Satoshi Okochi, Ryo Ogawara, Yuichi Sato, Shunsuke Miura, Tetsuro Yokokawa, Saori Miura, Koki Ueda, Masayoshi Oikawa, Akiomi Yoshihisa, Kazuhiko Ikeda, Takafumi Ishida, Yasuchika Takeishi

This study shows that macrophage extracellular traps (METs) contribute to heart failure by promoting cardiac remodelling through PAD4-dependent mechanisms, and targeting METs may offer therapeutic potential.

bioRxiv · Mar 18, 2026 · PreprintPathology

Genetic lineage of the Amami islanders inferred from classical genetic markers

Yuri Nishikawa, Takafumi Ishida

This study analyzes genetic markers in Amami islanders to determine their genetic relationship to mainland Japan and Okinawa, finding intermediate mtDNA and Y-STR profiles but distinct autosomal SNP frequencies.

Meta Gene · Dec 1, 2021Peer-reviewedGenetics