Hiromu Monai

Microglia-astrocyte interaction underlies aquaporin-4 dysregulation in the mouse cortex

This study shows that microglial activation mediates β-AdR-induced AQP4 dysregulation in the mouse cortex, revealing a microglia-astrocyte interaction in water homeostasis.

Immediate glucose signaling transmitted via the vagus nerve in gut-brain neural communication

The paper investigates how glucose signaling through the vagus nerve and frontal cortex affects sucrose preference in mice, showing the role of SGLT1, dopamine receptors, and stress.

Transcranial direct current stimulation alters cerebrospinal fluid-interstitial fluid exchange in mouse brain

This study shows that tDCS increases CSF-ISF exchange and metabolic waste efflux in mice, linked to astrocytic IP3/Ca2+ signaling and delta wave changes.

Aquaporin-4 dependent glymphatic solute transport in rodent brain

This study confirms that AQP4 is essential for glymphatic fluid and solute transport in the rodent brain, as Aqp4 disruption reduces CSF influx and amyloid-beta efflux.