Author

Virginia Plá

University of CopenhagenORCID 0000-0002-5501-0789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Maiken NedergaardiD· 3 shared Yuki MoriiD· 2 shared Alexander Stanley ThraneiD· 1 shared Anna L. R. XavieriD· 1 shared Antonio Ladrón-de-GuevaraiD· 1 shared Aravind AsokaniD· 1 shared Benjamin A. PlogiD· 1 shared Benjamin T. KressiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Maiken NedergaardORCID

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3 papers

Recent·Most cited

Glymphatic clearance is enhanced during sleep

Erik Kroesbergen, Laurence V. Riesselmann, Ryszard S. Gomolka, Virginia Plá, Tina Esmail, Visti Hildebrandt Stenmo, Eszter Rebeka Kovacs, Elise Schiøler Nielsen, Steven A. Goldman, Maiken Nedergaard, Pia Weikop, Yuki Mori

This study shows glymphatic clearance is increased during sleep and anesthesia and reduced during wakefulness, with tracer dose adjustments needed for accurate comparison across brain states.

bioRxiv · Aug 24, 2024 · PreprintNeuroscience

Structural characterization of SLYM - a 4th meningeal membrane

Virginia Plá, Styliani Bitsika, Michael J. Giannetto, Antonio Ladrón-de-Guevara, Daniel Gahn‐Martinez, Yuki Mori, Maiken Nedergaard, Kjeld Møllgård

The paper identifies and characterizes SLYM, a potential fourth meningeal membrane, using imaging and histological analysis in mice.

Fluids and Barriers of the CNS · Dec 14, 2023Peer-reviewedNeuroscience

Aquaporin-4 dependent glymphatic solute transport in rodent brain

Humberto Mestre, Lauren M. Hablitz, Anna L. R. Xavier, Weixi Feng, Wenyan Zou, Tinglin Pu, Hiromu Monai, Giridhar Murlidharan, Ruth M. Castellanos Rivera, Matthew J. Simon, Martin M. Pike, Virginia Plá, Ting Du, Benjamin T. Kress, Xiaowen Wang, , Maiken Nedergaard

This study confirms that AQP4 is essential for glymphatic fluid and solute transport in the rodent brain, as Aqp4 disruption reduces CSF influx and amyloid-beta efflux.

eLife · Dec 18, 2018Peer-reviewedNeuroscience