Author

Asha S. Multani

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-6989-8627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ahsan Saleem FarooqiiD· 1 shared Akdes Serin HarmancıiD· 1 shared Alexander J. LazariD· 1 shared Anand Kamal SinghiD· 1 shared Angela D. BhallaiD· 1 shared Anna RosenbaumiD· 1 shared Anthony Paul ConleyiD· 1 shared Arif O. HarmanciiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Ahsan Saleem FarooqiORCID

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2 papers

Recent·Most cited

ATRX Loss Predicts Poor Outcomes and Reveals a Therapeutic Vulnerability to TEAD Inhibition in Soft Tissue Sarcomas

Ryan A. Denu, Anand Kamal Singh, Yingda Jiang, Zhao Zheng, Davis R. Ingram, Khalida Wani, Rossana Lazcano, Madison P. Ginn, Kumaren Anand, Bishal K. Singh, Jackson C. Ballard, Veena Kochat, Biji Chatterjee, William I. Padron, Sharon M. Landers, , Kunal Rai

This study shows ATRX loss in sarcomas correlates with poor outcomes and identifies TEAD inhibition as a potential therapy for ATRX-deficient tumors.

bioRxiv · Nov 23, 2025 · PreprintCancer Biology

Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability

Rachel Naomi Curry, Malcolm F. McDonald, Peihao He, Brittney Lozzi, Yeunjung Ko, Isabella O’Reilly, Anna Rosenbaum, Wookbong Kwon, Leyla E. Fahim, Joshua M. Marcus, Noah Powell, Su Wang, Jin Ma, Asha S. Multani, Dong‐Joo Choi, , Ganesh S. Rao

This study shows that mutant IDH impairs PDGFB's chromatin binding, leading to chromosome instability and accelerated gliomagenesis.

bioRxiv · Feb 20, 2025 · PreprintCancer Biology