Martine Vrijheid

This study constructs a high-resolution placental mQTL resource and investigates how placental DNA methylation relates to early- and later-life traits and their shared vulnerability.

This paper develops a mechanistic NG-PBK model for PFOA using in vitro and in silico data, showing it accurately predicts toxicokinetics and can be extrapolated to other PFAS for risk assessment.

The paper identifies placental DNA methylation (DNAm) as a potential mediator of genetic risk for schizophrenia, bipolar disorder, and major depressive disorder using mQTL and GWAS data.

This study identifies genetic variants associated with urinary phthalate metabolite levels in children through GWAS and CNV analysis.

This study identifies genetic links between early vocabulary development and ADHD and cognition traits using genome-wide analyses.

This paper identifies 39,749 autosomal cis-eQTMs in children's blood using HELIX data, showing most are near genes and many have genetic variants associated with methylation and expression.

This paper identifies DNA methylation sites associated with aggression through a meta-analysis of epigenome-wide studies across different age groups and tissues.

The paper identifies 9 novel genetic loci, including low-frequency variants in TP53, associated with head circumference and intracranial volume in up to 46,000 individuals.

This study identifies a fetal genome-wide association signal near pro-inflammatory cytokine genes on 2q13 linked to gestational duration and preterm/postterm birth.