Malcolm John McConville

This paper introduces a workflow for integrating spatial transcriptomics and metabolomics data to analyze glioma tissue, identifying novel biological features at the tumor's infiltrating edge.

This study compares how two intralysosomal pathogens, C. burnetii and L. mexicana, affect lysosomal proteolytic activity and proteome changes in host cells.

This study shows that apicoplast-derived isoprenoids are essential for GPI anchor biosynthesis in Plasmodium falciparum, which is critical for parasite egress and invasion.

This paper describes the discovery of a marine sponge-associated mycobacterium closely related to M. tuberculosis, which shares virulence factors but lacks virulence in mice.

The paper compares matrix, deposition technique, and polarity settings in MALDI-TOF mass spectrometry imaging for brain tumors, finding recrystallized cyano-4-hydroxycinnamic acid in positive polarity provides best performance.