Author

Yan Wang

Augusta UniversityORCID 0000-0002-7136-9353Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yan Wang19 papers · Chinese Academy of Sciences

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Klaus F. LeyiD· 3 shared Mikhail FominiD· 2 shared Qingkang LyuiD· 2 shared Smriti ParashariD· 2 shared Andreas J. R. HabenichtiD· 1 shared Anusha BellapuiD· 1 shared Axel ImhofiD· 1 shared Changjun Yin· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Klaus F. LeyORCID

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3 papers

Recent·Most cited

Atherosclerosis destabilizes regulatory T cells (Tregs) resulting in multiple families of exTregs

Qingkang Lyu, Yan Wang, Anusha Bellapu, Polina Bombina, Sunil Kumar, Lauren Fogel, Smriti Parashar, Kunzhe Dong, Jiang Zhou, Devadatta Gosavi, Mikhail Fomin, Klaus F. Ley

This study identifies Treg destabilization as a staged differentiation process in atherosclerosis, leading to diverse exTreg states driven by IL-6R signaling.

bioRxiv · Jul 28, 2026 · PreprintImmunology

Talin-1 determines the direction of primary mouse neutrophils migrating in vivo

Yan Wang, Qingkang Lyu, Smriti Parashar, Mikhail Fomin, Pei Xiong Liew, Mark H. Ginsberg, Klaus F. Ley

This study uses EGFP-talin1 knock-in mice to show talin-1 dynamics during neutrophil migration in vivo, revealing its polarization during directional movement.

bioRxiv · May 31, 2026 · PreprintImmunology

Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis

Chuankai Zhang, Xi Zhang, Yi Ran, Zhihua Wang, Liping Li, Shu Wang, Junjie Zheng, Yixin Zhang, Ting Sun, Yutao Li, Shu Lu, Mingyang Hong, Zhe Ma, Sabine Steffens, Michael Hristov, , Changjun Yin

The paper identifies self-reactive B cells in atherosclerosis-associated tertiary lymphoid organs that produce high-affinity autoantibodies contributing to disease progression.

bioRxiv · Jul 10, 2025 · PreprintImmunology