Author

Komal Soni

Heidelberg UniversityORCID 0000-0002-7160-3189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Attila HorváthiD· 2 shared Irmgard SinningiD· 2 shared Klemens WildiD· 2 shared Tamás FischeriD· 2 shared Anusree Sivadas· 1 shared Bernd SimoniD· 1 shared Dirk FlemmingiD· 1 shared Henning UrlaubiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Attila HorváthORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Structures of aberrant spliceosome intermediates on their way to disassembly

Komal Soni, Attila Horváth, Olexandr Dybkov, Merlin Schwan, Sasanan Trakansuebkul, Dirk Flemming, Klemens Wild, Henning Urlaub, Tamás Fischer, Irmgard Sinning

The paper reports cryo-EM structures of aberrant spliceosome intermediates in S. pombe, revealing how a helicase-protein pair maintains catalytic dormancy and facilitates disassembly.

Nature Structural & Molecular Biology · Jan 20, 2025Peer-reviewedBiochemistry

Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.

Komal Soni, Anusree Sivadas, Attila Horváth, Nikolay Dobrev, Rippei Hayashi, L. Kiss, Bernd Simon, Klemens Wild, Irmgard Sinning, Tamás Fischer

This study identifies the interaction between Pla1 and Red1 in the MTREC complex and shows its role in polyadenylation of CUTs and heterochromatic island assembly.

Nature Communications · Feb 11, 2023Peer-reviewedMolecular Biology