Nikolay Dobrev

Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex.

This study identifies the interaction between Pla1 and Red1 in the MTREC complex and shows its role in polyadenylation of CUTs and heterochromatic island assembly.

The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery

This study shows Lem2, an inner nuclear membrane protein in S. pombe, recruits exosome co-factors to the nuclear periphery to regulate RNA degradation and coordinate transcripts during the mitosis-to-meiosis switch.

Mechanism of riboregulation of p62 protein oligomerisation by vault RNA1-1 in selective autophagy

The paper identifies the molecular mechanism by which vault RNA1-1 regulates p62 oligomerisation, essential for selective autophagy.

Fast and inexpensive whole genome sequencing library preparation from intact yeast cells

The paper describes a fast, low-cost method for preparing whole-genome sequencing libraries from yeast cells, enabling high-throughput analysis of genetic edits and polymorphisms.