Bernd Simon

This study shows that RNA recognition by the Sxl protein depends on a dynamic conformational ensemble rather than a single structure, and perturbing this balance impairs RNA binding.

This study investigates how ParB activates ParA ATPase activity during bacterial chromosome segregation in Myxococcus xanthus by analyzing their molecular interactions.

The paper shows Staufen directly interacts with Tm1 to regulate oskar mRNA transport by modulating kinesin-1 activity in Drosophila oocytes.

This paper identifies the RNA binding specificity of Hrp48, showing it binds the msl-2 mRNA 3' UTR independently of Sxl and Unr downstream of their binding sites.

This study identifies the interaction between Pla1 and Red1 in the MTREC complex and shows its role in polyadenylation of CUTs and heterochromatic island assembly.

The paper shows how multiple RNA binding domains in Unr mediate poly(A) specificity and interact with poly(A) binding protein during translation regulation.

The paper characterizes the quaternary hunchback mRNA repression complex formed by Brat, Pum, and Nanos, revealing its flexibility and independent binding of RNA components.

This study reveals how hnRNP A1 binds to the terminal loop of pri-mir-18a, destabilizing stem base-pairing to enhance miRNA processing.