Tamás Fischer

The paper reports cryo-EM structures of aberrant spliceosome intermediates in S. pombe, revealing how a helicase-protein pair maintains catalytic dormancy and facilitates disassembly.

This study identifies the interaction between Pla1 and Red1 in the MTREC complex and shows its role in polyadenylation of CUTs and heterochromatic island assembly.

This study shows Lem2, an inner nuclear membrane protein in S. pombe, recruits exosome co-factors to the nuclear periphery to regulate RNA degradation and coordinate transcripts during the mitosis-to-meiosis switch.