Sofie Ulfbeck Schovsbo

This study identifies cholesterol biosynthesis as a therapeutic target in CEBPA-mutant AML, showing that statins enhance chemosensitivity in cells with co-mutations in TET2 or WT1.

This study uses a ubiquitin replacement strategy to show K29-linked ubiquitylation regulates SUV39H1 stability and H3K9me3 levels in human cells.

The paper introduces iDIA, a method that enhances sensitivity for quantifying regulatory proteins in single cells, revealing lineage priming and cell-cycle coordination in hematopoietic stem and progenitor cells.