Author

Isabelle Chemin

Centre National de la Recherche ScientifiqueORCID 0000-0002-7188-5489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Chloé GoldsmithiD· 3 shared Héctor Hernández‐VargasiD· 3 shared Barbara TestoniiD· 2 shared María Guadalupe MartíneziD· 2 shared Anaëlle Dubois· 1 shared Anne CorluiD· 1 shared Audrey Diederichs· 1 shared Caroline CharreiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenomics

Chloé GoldsmithORCID

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3 papers

Recent·Most cited

Helicases DDX5 and DDX17 promote Hepatitis B Virus transcription termination heterogeneity in infected human hepatocytes

Fleur Chapus, Guillaume Giraud, Pélagie Huchon, Caroline Charre, Chloé Goldsmith, Mélanie Rodà, María Guadalupe Martínez, Judith Fresquet, Audrey Diederichs, Maëlle Locatelli, Hélène Polvèche, Xavier Grand, Caroline Scholtès, Isabelle Chemin, Héctor Hernández‐Vargas, , Barbara Testoni

The paper identifies DDX5 and DDX17 as factors promoting HBV transcriptional readthrough and affecting viral RNA stability and replication.

bioRxiv · Jan 17, 2024 · PreprintMolecular Biology

Epigenetic heterogeneity after de novo assembly of native full-length Hepatitis B Virus genomes

Chloé Goldsmith, Damien Cohen, Anaëlle Dubois, María Guadalupe Martínez, Kilian Petitjean, Anne Corlu, Barbara Testoni, Héctor Hernández‐Vargas, Isabelle Chemin

The paper develops a method to detect 5mCpG in HBV genomes without bisulfite conversion, enabling de novo assembly and identification of epigenetic clusters in infected patients.

bioRxiv · May 29, 2020 · PreprintGenomics

Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro hepatocyte differentiation

Jesús Rafael Rodríguez‐Aguilera, Szilvia Ecsedi, Marie‐Pierre Cros, Chloé Goldsmith, Mariana Domínguez-López, Nuria Guerrero‐Celis, Rebeca Pérez‐Cabeza de Vaca, Isabelle Chemin, Félix Recillas Targa, Victoria Chagoya de Sánchez, Héctor Hernández‐Vargas

The paper shows that 5-hydroxymethylcytosine (5hmC) increases genome-wide during early hepatocyte differentiation and its modulation affects hepatic identity markers.

bioRxiv · May 7, 2019 · PreprintGenomics