Barbara Testoni

This study evaluates precision-cut liver slices as an ex vivo model for studying HBV/HDV co-infection and testing antiviral agents.

This study uses adenine base editing to target HBV DNA and suppress HBsAg production and HDV release in vitro and in vivo.

This study shows DDX5 and DDX17 regulate HBV RNA splicing, affecting viral protein expression and liver disease progression.

Bolero is a computational workflow for analyzing HBV long-read sequencing data to quantify viral RNA transcripts and spliced variants, enabling study of cccDNA transcriptional activity.

The paper identifies DDX5 and DDX17 as factors promoting HBV transcriptional readthrough and affecting viral RNA stability and replication.

The paper develops a method to detect 5mCpG in HBV genomes without bisulfite conversion, enabling de novo assembly and identification of epigenetic clusters in infected patients.