Zongan Wang

The genetic repertoire of the deep sea: from sequence to structure and function

This study analyzes the genetic diversity of the deep sea, linking protein structures to genetic variants and identifying biotechnologically relevant features.

ExMODE: A Multi-Omics Repository for Extremophile Adaptation and Bioprospecting

ExMODE is a multi-omics database for extremophiles that integrates and standardizes data to enable comparative analysis and bioprospecting.

NanoporeDB: A Structural Resource Of Multimeric Protein Nanopores In Single-Molecule Sensing

NanoporeDB is a structural database of multimeric protein nanopores, providing 3D models and quantitative metrics to support nanopore-based sensing and synthetic biology.

A deep learning and co-conservation framework enable discovery of non-canonical Cas proteins

The paper introduces BioPrinCRISPR, a framework to identify and characterize CRISPR-Cas systems, revealing non-canonical variants and novel domain architectures across bacterial genomes.

A single-molecule nanopore sequencing platform

This paper introduces an improved nanopore sequencing platform called CycloneSEQ, demonstrating long-duration sequencing and high yield with applications in genomics.