Author

Noah Reis

Stanford MedicineORCID 0000-0002-7258-2463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Sergiu P. PașcaiD· 4 shared James P. McQueeniD· 3 shared Ji‐il KimiD· 2 shared Kevin W. KelleyiD· 2 shared Massimo M. OnestoiD· 2 shared Neal D. AminiD· 2 shared Sabina KantoniD· 2 shared Shravanti Kulkarni· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersNeuroscience

Sergiu P. PașcaORCID

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Author profile →

4 papers

Recent·Most cited

Human neuromodulatory assembloids to study serotonin signaling and disease

Sabina Kanton, Xiangling Meng, Chunyang Dong, Fikri Birey, Dong Wang, Noah Reis, Se‐Jin Yoon, Ji‐il Kim, James P. McQueen, Noriaki Sakai, Seiji Nishino, John R. Huguenard, Sergiu P. Pașca

This study creates human neuromodulatory assembloids to investigate serotonin signaling and disease mechanisms, showing altered 5-HT dynamics in 22q11.2DS and rescue with SSRIs.

bioRxiv · Mar 10, 2026 · PreprintNeuroscience

Midline Assembloids Reveal Regulators of Human Axon Guidance

Massimo M. Onesto, Neal D. Amin, Chenjie Pan, Xiaoyu Chen, Ji‐il Kim, Noah Reis, Sabina Kanton, Alfredo M. Valencia, Zuzana Hudáčová, James P. McQueen, Marc Tessier‐Lavigne, Sergiu P. Pașca

The paper develops a human midline assembloid model to study axon guidance and identifies GALNT2 as a human-specific regulator of commissural axon guidance.

Science · Jul 17, 2025Peer-reviewedNeuroscience

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Konstantin Kaganovsky, Massimo M. Onesto, Jin Hao, Yuki Miura, James P. McQueen, Noah Reis, Genta Narazaki, Tommy Li, Shravanti Kulkarni, Sergey D. Pavlov, Sergiu P. Pașca

This study uses a morphogen screen in human neural organoids to generate diverse neural cell types and uncover design principles of brain region specification.

Cell stem cell · Dec 1, 2024Peer-reviewedNeuroscience

CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development

Xiangling Meng, David Yao, Kent Imaizumi, Xiaoyu Chen, Kevin W. Kelley, Noah Reis, Mayuri Vijay Thete, Arpana Arjun McKinney, Shravanti Kulkarni, Georgia Panagiotakos, Michael Cory Bassik, Sergiu P. Pașca

The paper uses CRISPR screens in human forebrain assembloids to identify NDD genes involved in interneuron generation and migration, revealing novel roles for the ER in migration.

Nature · Sep 27, 2023Peer-reviewedNeuroscience