Xiaoyu Chen

The paper describes a human assembloid model to study enterovirus pathogenesis, showing that different EVs cause muscle contraction loss through distinct cellular mechanisms.

The paper investigates a human-specific VNTR in CACNA1C and shows it modulates neuronal calcium responses and transcription programs.

This paper introduces a color-neutral and reversible tissue transparency method that enables longitudinal deep-tissue imaging in live mice with high spatiotemporal resolution.

The paper develops a human midline assembloid model to study axon guidance and identifies GALNT2 as a human-specific regulator of commissural axon guidance.

The paper develops an assembloid model of the human cortico-striatal-thalamic-cortical circuit to study its function and disease-related disruptions.

This paper introduces kirigami electronics for long-term, minimally-invasive electrophysiological recording of human neural organoids and assembloids in suspension.

The paper uses CRISPR screens in human forebrain assembloids to identify NDD genes involved in interneuron generation and migration, revealing novel roles for the ER in migration.

The paper profiles midgestation human spinal cord cells at single-cell resolution, revealing early diversification of motor neurons and glial cell types.