Author

Stefano Cacchione

Sapienza University of RomeORCID 0000-0002-7278-3695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Grazia Daniela RaffaiD· 3 shared Livia Scatolini· 3 shared Maurizio GattiiD· 3 shared Paolo MaccalliniiD· 3 shared Alessio ColantoniiD· 2 shared Cristiano De PittàiD· 2 shared Francesca Bavasso· 2 shared Gabriele Proietti· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Grazia Daniela RaffaORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintApr 17, 2025

RNase H1 counteracts DNA damage and ameliorates SMN-dependent phenotypes in a Drosophila model of Spinal Muscular Atrophy

Livia Scatolini, Lucia Graziadio, Damiano Guerrini…·Grazia Daniela Raffa

This study shows that RNase H1 reduces DNA damage and improves SMA-like symptoms in a Drosophila model by resolving RNA:DNA hybrids caused by SMN deficiency.

DOI 10.1101/2025.04.17.649348

Drosophilaproteomics

𝕏 PostBluesky

GeneticsbioRxivPreprintOct 27, 2020

TGS1 controls snRNA 3' end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo

Lü Chen, Caitlin M. Roake, Paolo Maccallini…·Grazia Daniela Raffa

This study shows TGS1 is essential for snRNA 3' end processing and its loss causes neurodegeneration, which can be mitigated by human TGS1 expression in model organisms.

2 citations

C. elegansDrosophila

𝕏 PostBluesky

GeneticsPLoS GeneticsPeer-reviewedMay 26, 2020

Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Paolo Maccallini, Francesca Bavasso, Livia Scatolini…·Grazia Daniela Raffa

This study identifies functional interactions between TGS1 and the Smn complex in Drosophila eye development, showing their roles in retinal progenitor cell viability and eye size.

10 citations

Drosophilaexperimental assay

𝕏 PostBluesky