Author

Mariana Alves

Royal College of Surgeons in IrelandORCID 0000-0002-7332-3682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alberto ParrasiD· 2 shared David Clifford HenshalliD· 2 shared Edward H. BeameriD· 2 shared Giorgia ConteiD· 2 shared Ivana OllàiD· 2 shared José J. LucasiD· 2 shared Laura de Diego-GarcíaiD· 2 shared Raúl MéndeziD· 2 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alberto ParrasORCID

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2 papers

Recent·Most cited

High concordance between hippocampal transcriptome of the intraamygdala kainic acid model and human temporal lobe epilepsy

Giorgia Conte, Alberto Parras, Mariana Alves, Ivana Ollà, Laura de Diego-García, Edward H. Beamer, Razi Alalqam, Alejandro Ocampo, Raúl Méndez, David Clifford Henshall, José J. Lucas, Tobías Engel

The paper compares gene expression in a mouse model of status epilepticus to human temporal lobe epilepsy tissue, finding high concordance in gene dysregulation and shared molecular features.

Epilepsia · Oct 18, 2020Peer-reviewedNeuroscience

Large-scale changes to mRNA polyadenylation in temporal lobe epilepsy

Alberto Parras, Laura de Diego-García, Mariana Alves, Edward H. Beamer, Giorgia Conte, James Morgan, Ivana Ollà, Yasmina Hernandez-Santana, Norman Delanty, Michael A. Farrell, Donncha F. O’Brien, David Clifford Henshall, Raúl Méndez, José J. Lucas, Tobías Engel

This study identifies widespread changes in mRNA polyadenylation in temporal lobe epilepsy, highlighting the role of CPEB4 in seizure severity and neurodegeneration.

bioRxiv · Aug 8, 2019 · PreprintNeuroscience