Jianxiong Zeng

Activation of innate immune cGAS-STING pathway contributes to Alzheimer pathogenesis in 5xFAD mice

This study shows that the cGAS-STING pathway contributes to Alzheimer's disease progression in 5xFAD mice, and its inhibition reduces disease pathology.

Atp13a5 Marker Reveals Pericytes of The Central Nervous System in Mice

The paper identifies Atp13a5 as a specific marker for CNS pericytes in mice and develops a transgenic model to study their biology.

Microvascular Injury in Mild Traumatic Brain Injury Accelerates Alzheimer-like Pathogenesis in Mice

This study shows that microvascular injury from mild TBI accelerates Alzheimer-like pathology in mice, suggesting vascular repair could mitigate AD risk.