Marina Ortega-Zapero

Adaptive motility enables neutrophils to rapidly navigate confined capillaries

This study shows neutrophils maintain high migration speed in capillaries of varying sizes by adapting their actomyosin cytoskeleton via the ROCK-MyoII pathway, preventing vascular obstruction.

Lamin A/C regulates the compartment-specific contributions of immune and stromal cells to intestinal inflammation and colitis-associated colon cancer

This study identifies lamin A/C as a regulator of intestinal inflammation and tumorigenesis by modulating immune and stromal cell functions in mouse models and human IBD biopsies.

Segmental regulation of intestinal motility by colitis and the adaptive immune system in the ileum and colon

This study investigates how colitis and the adaptive immune system regulate intestinal motility in the ileum and colon using a mouse model.

Role of Lamin A/C on dendritic cell function in antiviral immunity

This study shows that lamin A/C is essential for dendritic cell function in antiviral immunity by modulating epigenetic and transcriptional processes.