Author

Raquel Castillo‐González

Research Institute Hospital 12 de OctubreORCID 0000-0002-9877-2126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Agustín LahoziD· 1 shared Alberto Mora PerdigueroiD· 1 shared Ana García GarcíaiD· 1 shared Ángela SaéziD· 1 shared Antonio Giráldez Trujillo· 1 shared Aránzazu Cruz‐AdaliaiD· 1 shared Carlos del Pozo-RojasiD· 1 shared Clara Luque‐RiojaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperCancer Biology

Agustín LahozORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer

Ana García García, María Ferrer Aporta, Germán Vallejo-Palma, Antonio Giráldez Trujillo, Raquel Castillo‐González, David Calzón Lozano, Alberto Mora Perdiguero, Raúl Muñoz Velasco, Miguel Colina Castro, Elena de Simone Benito, Raúl Torres-Ruiz, Sandra Rodríguez, Jonas Dehairs, Johannes V. Swinnen, Juan Carlos García‐Cañaveras, , Victor Javier Sanchez-Arevalo Lobo

This study identifies ELOVL6 as a therapeutic target in pancreatic cancer by showing its role in c-MYC-driven lipid metabolism and its impact on chemotherapy efficacy.

Nature Communications · Feb 16, 2025Peer-reviewedCancer Biology

Segmental regulation of intestinal motility by colitis and the adaptive immune system in the ileum and colon

Raquel Gómez-Bris, Pilar Rodríguez‐Rodríguez, Marina Ortega-Zapero, Santiago Ruvira, Raquel Castillo‐González, María Jesús Fernández‐Aceñero, Aránzazu Cruz‐Adalia, Ángela Saéz, Silvia Magdalena Arribas, José María González

This study investigates how colitis and the adaptive immune system regulate intestinal motility in the ileum and colon using a mouse model.

American Journal Of Pathology · Nov 17, 2024Peer-reviewedImmunology