Author

Louis Robert Villeneuve

Montreal Heart Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1

Frequent Co-Authors

Adnane SellamiD· 2 shared Antony T. VincentiD· 2 shared Andrew Chatr‐aryamontriiD· 1 shared Anna NozzaiD· 1 shared Chloé Lévesque· 1 shared Dobromir DobreviD· 1 shared Donald M. BersiD· 1 shared Éric RhéaumeiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

Adnane SellamORCID

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Author profile →

4 papers

Recent·Most cited

Isw2-mediated chromatin remodeling governs antifungal tolerance and heteroresistance in Candida albicans

María Juliana Mantilla, Faïza Tebbji, Antony T. Vincent, Louis Robert Villeneuve, Andrew Chatr‐aryamontri, Adnane Sellam

This study identifies Isw2-mediated chromatin remodeling as a regulator of antifungal tolerance and heteroresistance in Candida albicans, revealing its role in suppressing CRZ1 transcription and modulating drug responses.

bioRxiv · Apr 22, 2026 · PreprintMicrobiology

Manganese homeostasis modulates glucan and chitin unmasking in the opportunistic yeast Candida albicans

Manon Henry, Maria Khouas, Gabriel Théberge-Julien, Antony T. Vincent, Louis Robert Villeneuve, Éric Rhéaume, Jean‐Claude Tardif, Adnane Sellam

This study shows that manganese homeostasis in Candida albicans affects cell wall integrity and antigen exposure, altering immune recognition.

Virulence · Oct 8, 2025Peer-reviewedMicrobiology

Inflammatory bowel disease risk gene C1ORF106 regulates actin dynamics in intestinal epithelial cells

Isabelle Hébert-Milette, Chloé Lévesque, Jean Paquette, Marie-Ève Rivard, Louis Robert Villeneuve, Gabrielle Boucher, Philippe Goyette, Guy Charron, John David Rioux

This study shows that C1ORF106 and its IBD variant regulate intestinal barrier permeability by controlling tight junctions, cell polarity, and F-actin dynamics through a ROCK-dependent mechanism.

bioRxiv · Mar 14, 2025 · PreprintGenetics

Time-dependent Mitochondrial Remodeling in Experimental Atrial Fibrillation and Potential Therapeutic Relevance

Xiaoyan Qi, Feng Xiong, Jiening Xiao, Kalai Mangai Muthukumarasamy, Yasemin Altuntaş, Yuan Zhong, Issam Abu-Taha, Florian Bruns, Marcel A. Tekook, Markus Kamler, Louis Robert Villeneuve, Anna Nozza, Martin G. Sirois, Jason M. Karch, Philippe Pasdois, , Stanley Nattel

This study examines mitochondrial changes during atrial fibrillation in animals and humans, showing early hyperfunction and damage, and demonstrates that mitochondrial-targeted therapy can prevent adverse remodeling and AF sustainability.

bioRxiv · Jan 29, 2025 · PreprintPathology