Induced alanine auxotrophy as a therapeutic strategy against Mycobacterium tuberculosis
Menna-Allah W. Shalaby, Nagabhushana C. Beeralingappa, Annadka Shrinidhi…·Michaelle Chojnacki
The paper identifies TI-374 and TI-801 as inhibitors of Mycobacterium tuberculosis's AlaA enzyme, showing their efficacy against intracellular Mtb and supporting AlaA as a therapeutic target.