Author

Sanjana B. Shah

Broad InstituteORCID 0000-0002-7389-328XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Steven P. GygiiD· 2 shared Aditi Swamy· 1 shared Adrian R. KraineriD· 1 shared Anand VasudevaniD· 1 shared Andrea ArrudaiD· 1 shared Andrew Chatr‐aryamontriiD· 1 shared Brianna E. MendelsoniD· 1 shared Claudia A. MimosoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Steven P. GygiORCID

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2 papers

Recent·Most cited

Cancer BiologyBloodPeer-reviewedSep 24, 2025

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias

Travis J. Fleming, Mateusz Antoszewski, Sander Lambo…·Vijay G. Sankaran

This study identifies MECOM's role in blocking differentiation via CEBPA repression, showing that targeting this regulatory element can promote differentiation and reduce leukemia burden in AMLs.

11 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintAug 3, 2025

On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions

Linda Julian, Lisa Crozier, Devon A. Lukow…·Jason M. Sheltzer

This study shows CDK11 is critical for cancer cell survival and identifies 1p36 deletions as a biomarker for CDK11 inhibitor sensitivity, but on-target toxicity limits therapeutic efficacy.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky