Author

Yunlong Xiang

Center for Life SciencesORCID 0000-0002-7481-7174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Wei XieiD· 2 shared Anna‐Katerina HadjantonakisiD· 1 shared Chantriolnt-Andreas KapouraniiD· 1 shared Christel KruegeriD· 1 shared Cong Lyu· 1 shared Courtney W. HannaiD· 1 shared Felix KruegeriD· 1 shared Florian BuettneriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersDevelopmental Biology

Wei XieORCID

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2 papers

Recent·Most cited

ZFP281 coordinates DNMT3 and TET1 for transcriptional and epigenetic control in pluripotent state transitions

Xin Huang, Sophie Balmer, Cong Lyu, Yunlong Xiang, Vikas Malik, Hailin Wang, Yu Zhang, Wei Xie, Anna‐Katerina Hadjantonakis, Hongwei Zhou, Jianlong Wang

This study identifies ZFP281 as a coordinator of DNMT3A/3B and TET1 to regulate DNA methylation and gene expression during pluripotent stem cell state transitions.

bioRxiv · Mar 24, 2023 · PreprintDevelopmental Biology

Single cell multi-omics profiling reveals a hierarchical epigenetic landscape during mammalian germ layer specification

Ricard Argelaguet, Hisham Mohammed, Stephen J. Clark, L. Carine Stapel, Christel Krueger, Chantriolnt-Andreas Kapourani, Yunlong Xiang, Courtney W. Hanna, Sébastien A. Smallwood, Ximena Ibarra-Soria, Florian Buettner, Guido Sanguinetti, Felix Krueger, Wei Xie, Peter J. Rugg‐Gunn, , Wolf Reik

The paper uses single cell triple-omics analysis to reveal how epigenetic changes drive germ layer specification in mouse embryos, showing distinct epigenetic priming and remodeling in different lineages.

bioRxiv · Jan 13, 2019 · PreprintDevelopmental Biology