Author

Jelmer Willems

Utrecht UniversityORCID 0000-0002-7563-1785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein design· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Arthur P.H. de JongiD· 2 shared Harold D. MacGillavryiD· 2 shared Eline Jasmijn MertensiD· 1 shared Frank Julius MeyeiD· 1 shared Fred de WinteriD· 1 shared Joost VerhaageniD· 1 shared Lisa A.E. CatsburgiD· 1 shared Nicky ScheefhalsiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Arthur P.H. de JongORCID

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2 papers

Recent·Most cited

Multiplex labeling and manipulation of endogenous neuronal proteins using sequential CRISPR/Cas9 gene editing

Wouter J. Droogers, Jelmer Willems, Harold D. MacGillavry, Arthur P.H. de Jong

This paper introduces CAKE, a method for multiplex CRISPR/Cas9 gene editing in neurons to label and manipulate endogenous proteins with high accuracy and low crosstalk.

eNeuro · Jul 1, 2022Peer-reviewedNeuroscience

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Jelmer Willems, Arthur P.H. de Jong, Nicky Scheefhals, Eline Jasmijn Mertens, Lisa A.E. Catsburg, Rogier B. Poorthuis, Fred de Winter, Joost Verhaagen, Frank Julius Meye, Harold D. MacGillavry

ORANGE enables targeted genomic integration of fluorescent tags in neurons to study endogenous protein distribution with high-resolution imaging.

PLoS Biology · Apr 10, 2020Peer-reviewedNeuroscience