Author

Rogier B. Poorthuis

Utrecht UniversityORCID 0000-0002-7292-4072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Assay:imaging· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Frank Julius MeyeiD· 2 shared A. S. J. NicolsoniD· 1 shared Anna SchroederiD· 1 shared Annemieke Benschop· 1 shared Arthur P.H. de JongiD· 1 shared Danai RigaiD· 1 shared Eline Jasmijn MertensiD· 1 shared Fred de WinteriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Frank Julius MeyeORCID

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Author profile →

3 papers

Recent·Most cited

A prefrontal cortex-lateral hypothalamus circuit controls stress-driven increased food intake

Laura. F. Supiot, Karlijn L. Kooij, W. Du, Annemieke Benschop, A. S. J. Nicolson, R. Haak, Inge G. Wolterink‐Donselaar, Mieneke C. M. Luijendijk, Danai Riga, Roger A.H. Adan, Rogier B. Poorthuis, Frank Julius Meye

This study identifies a prefrontal cortex-lateral hypothalamus circuit that mediates stress-driven increased food intake in mice.

Nature Communications · Mar 31, 2026Peer-reviewedNeuroscience

Layer 1 NDNF Interneurons are Specialized Top-Down Master Regulators of Cortical Circuits

Jan Hartung, Anna Schroeder, Rodrigo Alejandro Péréz Vázquez, Rogier B. Poorthuis, Johannes J. Letzkus

This study identifies NDNF-expressing layer 1 interneurons as top-down master regulators of cortical circuits through widespread inhibition of deeper layer interneurons and unique physiological properties.

Cell Reports · May 1, 2024Peer-reviewedNeuroscience

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Jelmer Willems, Arthur P.H. de Jong, Nicky Scheefhals, Eline Jasmijn Mertens, Lisa A.E. Catsburg, Rogier B. Poorthuis, Fred de Winter, Joost Verhaagen, Frank Julius Meye, Harold D. MacGillavry

ORANGE enables targeted genomic integration of fluorescent tags in neurons to study endogenous protein distribution with high-resolution imaging.

PLoS Biology · Apr 10, 2020Peer-reviewedNeuroscience