Alessandra Romanelli

Identification of ICAM-1-targeting DNA aptamers as a host-directed strategy to inhibit Human Rhinovirus infection

This paper identifies DNA aptamers targeting ICAM-1 to inhibit HRV infection by blocking viral entry, showing concentration-dependent antiviral effects in vitro.

Amphibian-derived peptide analog TB_KKG6K: A powerful drug candidate against Candida albicans with anti-biofilm efficacy

This study identifies TB_KKG6K, an amphibian-derived peptide, as a potent antifungal agent effective against Candida albicans planktonic cells and biofilms, with no adverse effects on standard antifungal drugs.

Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 RNPs

This paper demonstrates efficient CRISPR-Cas9-based gene disruption in the medfly using RNPs, achieving high germline transmission and mutant phenotypes.