Author

Murugappan Ramanathan

Johns Hopkins UniversityORCID 0000-0002-7612-9586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew P. LaneiD· 3 shared Nicholas R. RowaniD· 3 shared Fernando Tadeu ZamunériD· 2 shared Kenny VuiD· 2 shared Nyall R. LondoniD· 2 shared Sreenivasulu Gunti· 2 shared Aaron M. UdageriD· 1 shared Alexander T. HilleliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersGenomics

Andrew P. LaneORCID

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3 papers

Recent·Most cited

scRNA-seq and genomics analyses reveal key mechanisms of inverted papilloma-associated sinonasal squamous cell carcinoma malignant transformation

Tolani F. Olonisakin, Fernando Tadeu Zamunér, Kenny Vu, Sreenivasulu Gunti, Y M Ding, Yue Hou, Xinping Yang, Ramya Viswanathan, Angel Huynh, Federico Comoglio, Marco Notaro, Christopher Cherry, Michael Patatanian, Nathan W. Wong, Timothy R. DeKlotz, , Nyall R. London

This study identifies molecular and immune mechanisms driving malignant transformation from inverted papilloma to sinonasal squamous cell carcinoma using multi-omics analyses.

bioRxiv · Jun 4, 2026 · PreprintGenomics

Molecular patterns and mechanisms of tumorigenesis in HPV-associated and HPV-independent sinonasal squamous cell carcinoma

Fernando Tadeu Zamunér, Sreenivasulu Gunti, Gabriel J. Starrett, Farhoud Faraji, Tiffany Toni, Anirudh Saraswathula, Kenny Vu, Anuj Kumar Gupta, Yan Zhang, Daniel L. Faden, Michael E. Bryan, Theresa W. Guo, Nicholas R. Rowan, Murugappan Ramanathan, Andrew P. Lane, , Nyall R. London

This study identifies molecular differences between HPV-associated and HPV-independent SNSCC, showing HPV drives tumorigenesis and suggesting YAP/TAZ and PI3K inhibition as therapeutic targets.

Nature Communications · Jun 11, 2025Peer-reviewedCancer Biology

Elevated ACE2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication

Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather M. Kulaga, Alexander T. Hillel, Murugappan Ramanathan, Andrew P. Lane

The paper identifies ACE2 enrichment in the olfactory neuroepithelium, linking it to SARS-CoV-2 entry, anosmia, and potential intranasal therapy targets.

European Respiratory Journal · Aug 18, 2020Peer-reviewedMolecular Biology