Mitsue Hagihara

This study creates a transcriptomic atlas of the Syrian hamster preoptic area using snRNA-seq and spatial transcriptomics, comparing seasonal and hibernation states.

The paper investigates how VPA exposure and OT neuron stimulation affect microglia in the PVH and finds that OT neuron activation can reverse some microglial gene downregulation.

This study shows hypothermia, not hypometabolism, suppresses reproductive activity in mice by reducing arcuate kisspeptin neuron activity during energy-saving conditions.

The paper identifies BSTpr Cartpt+ neurons as mediators of pup-directed aggression in male mice and shows their role in the transition to parental care.

The paper identifies vasopressin-to-oxytocin receptor crosstalk in the preoptic area as a key mechanism for paternal caregiving behaviors in male mice.

This study shows that artificially induced hypothermia during pregnancy in mice causes fetal growth impairment and pregnancy loss, highlighting the importance of maternal body temperature in fetal development.

The paper identifies the submedius thalamus (SMT) as a presynaptic partner of the orbitofrontal cortex (OFC) in mice, showing its role in modulating maternal behavior through experience-dependent plasticity.

This paper identifies RPa-vGluT3 neurons as critical regulators of thermogenesis by coordinating sympathetic and somatic motor outputs to increase body temperature.

The paper shows pregnancy in mice reduces excitatory inputs to PVH oxytocin neurons, promoting increased food intake by dampening their anorexigenic activity.

This study shows that the orbitofrontal cortex promotes alloparental caregiving in female mice by modulating dopamine dynamics during behavior acquisition.

This study shows that dietary availability affects puberty onset in female mice by modulating the activity of arcuate kisspeptin neurons through a neural circuit involving Agrp neurons.

The paper identifies two molecularly distinct subtypes of sympathetic preganglionic neurons in mice that selectively regulate gastrointestinal and adrenal functions through non-overlapping innervation patterns.

The paper shows that social dysfunction in mice is linked to selective gene expression impairment in parvocellular oxytocin neurons, which can be mitigated by neonatal chemogenetic stimulation.

The paper develops a Cre-free method to monitor oxytocin neuron activity in lactating mice and shows that pulsatile activity depends on mother-pup contact.

This study uses chronic in vivo Ca2+ imaging to track pulsatile activity of kisspeptin neurons in aging female mice, revealing robust frequency patterns but declining intensity during reproductive senescence.

The paper records and manipulates maternal oxytocin (OT) neural activities in mice using fiber photometry and identifies plasticity and modulatory circuits.

The paper identifies oxytocin neurons as key regulators of paternal caregiving in male mice and shows enhanced excitatory connections from lateral hypothalamus neurons in fathers.