Author

Reyhaneh Tirgar

National Institutes of HealthORCID 0000-0002-7618-2977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jared T. NordmaniD· 2 shared Amanda A. AmodeoiD· 1 shared Anna ZinovyevaiD· 1 shared Anusha D BhattiD· 1 shared Dustin Haskell· 1 shared Eli Coronado-ChaveziD· 1 shared Guoyun Yu· 1 shared Jonathan P. DaviesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Jared T. NordmanORCID

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3 papers

Recent·Most cited

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Mohit Das, Eli Coronado-Chavez, Anusha D Bhatt, Reyhaneh Tirgar, Amanda A. Amodeo, Jared T. Nordman

This study shows NASP prevents H3 aggregation in the cytoplasm, indirectly protecting H3 from degradation during early Drosophila embryogenesis.

The Journal of Cell Biology · Mar 31, 2026Peer-reviewedMolecular Biology

A noncanonical Pol III-dependent, Microprocessor-independent biogenesis pathway generates a germline enriched miRNA family

Rima M. Sakhawala, Reyhaneh Tirgar, Karl-Frédéric Vieux, Dustin Haskell, Guoyun Yu, Anna Zinovyeva, Katherine McJunkin

The paper identifies a noncanonical miRNA biogenesis pathway in C. elegans and humans that is Pol III-dependent, Microprocessor-independent, and Dicer-dependent, generating germline-enriched miRNAs like mir-1829 and miR-4521.

Genes & Development · Jul 14, 2025Peer-reviewedMolecular Biology

The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo

Reyhaneh Tirgar, Jonathan P. Davies, Lars Plate, Jared T. Nordman

This study identifies NASP as the critical H3-H4 histone chaperone in the Drosophila embryo, showing that its absence leads to degradation of soluble H3-H4 pools and embryonic defects.

PLoS Genetics · Mar 17, 2023Peer-reviewedDevelopmental Biology