Lise Dauban

The paper relocates promoter-reporter constructs to study the positional relationship between the Sox2 gene and its enhancer, revealing gene-mediated confinement of enhancer activity.

The paper investigates how genomic regions called LADs interact with the nuclear lamina, finding that these interactions are multivalent and cooperative, with some subregions having stronger affinity and influencing neighboring sequences.

The paper investigates how Scc2, Smc3 acetylation, and Pds5 regulate cohesin-dependent chromatin loop expansion during the cell cycle.

The paper identifies Eco1's role in negatively regulating cohesin translocase activity during yeast mitosis, affecting DNA loop extrusion and chromosome folding.