Tim-3 Promotes Early Differentiation of Tbet+ Effector T Cells During Acute Viral Infection
Priyanka Manandhar, Emily Landy, Kanako Mori, Larry Kane
bioRxiv · Jul 8, 2025 · PreprintImmunology
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Priyanka Manandhar, Emily Landy, Kanako Mori, Larry Kane
bioRxiv · Jul 8, 2025 · PreprintImmunology
Jemy Varghese, Emily Landy, Leonardo Huang, Anastasia Frank‐Kamenetskii, Hannah Klinghoffer, Jeremy A. Morrissette, Vinh Dang, Stephen D. Carro, Laurence Crane Eisenlohr, Scott Canna
This study shows IL-18 can induce both hyperinflammation and immunodeficiency in mice depending on the infectious trigger, leading to MAS and poor viral clearance.
bioRxiv · Jul 4, 2025 · PreprintImmunology