Author
Ontario Institute for Cancer ResearchORCID 0000-0002-7672-5783Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Uri Seroussi, Andrew Lugowski, Lina Wadi, Robert X. Lao, Alexandra R. Willis, Winnie Zhao, Adam E. Sundby, Amanda G. Charlesworth, Aaron W Reinke, Julie M. Claycomb
The paper systematically analyzes all 19 AGO proteins in C. elegans to uncover gene regulatory networks and novel phenotypes associated with their loss.
eLife · Feb 15, 2023Peer-reviewedMolecular Biology
Jüri Reimand, Ruth Isserlin, Véronique Voisin, Mike Kucera, Christian Tannus-Lopes, Asha Rostamianfar, Lina Wadi, Mona Meyer, J. D. Wong, Changjiang Xu, Daniele Merico, Gary D. Bader
Step-by-step protocol for interpreting omics gene lists via g:Profiler or GSEA enrichment testing, then grouping redundant enriched pathways into themes with Cytoscape Enrichment Map.
Nature Protocols · Jan 21, 2019Peer-reviewedBioinformatics✦ In-depth digest
Matthew A. Reyna, David Haan, Marta Paczkowska, Lieven P.C. Verbeke, Miguel Vazquez, Abdullah Kahraman, Sergio Pulido-Tamayo, Jonathan Barenboim, Lina Wadi, Priyanka Dhingra, Raunak Shrestha, Gad Getz, Michael S. Lawrence, Jakob Skou Pedersen, Mark A. Rubin, , on behalf of the PCAWG Drivers and Functional Interpretation Group and the ICGC/TCGA Pan-Cancer Analysis of Whole Genome Network
The paper analyzes non-coding mutations across 2,583 cancer genomes to identify genes and pathways affected, finding clusters of interacting proteins and insights into cancer mechanisms.
bioRxiv · Aug 7, 2018 · PreprintCancer Biology
Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Grace Tiao, Henrik Hornshøj, Julian M. Hess, Randi Istrup Pedersen, Lars Feuerbach, Radhakrishnan Sabarinathan, Tobias Lynge Madsen, Jaegil Kim, Loris Mularoni, Shimin Shuai, Andrés Lanzós, Carl Herrmann, , Gad A. Getz
The paper identifies and characterizes coding and non-coding driver mutations across 2,500 cancer genomes, revealing new candidates and questioning previous findings.
bioRxiv · Dec 23, 2017 · PreprintGenomics
Lina Wadi, Mona Meyer, Joel Weiser, Lincoln D Stein, Juri Reimand
The paper examines how evolving gene annotations affect pathway enrichment analysis, finding that outdated software misses most current enrichments.
bioRxiv · Apr 19, 2016Bioinformatics