Bogdan I. Florea

This study determines the structure of the mycobacterial LCC complex to elucidate its substrate selectivity and catalytic mechanism.

This study uses BONCAT to identify the proteome of S. aureus persisters under antibiotic stress, revealing upregulated pathways and downregulated processes involved in survival.

CellEKT profiles cellular target engagement of kinase inhibitors using chemical proteomics to determine IC50 values across over 300 kinases and validate results with phosphoproteomics and NanoBRET.

The paper quantifies host proteome dynamics during Salmonella infection, revealing cathepsin-dependent cell death mechanisms.

The paper identifies and characterizes novel catecholate-hydroxamate siderophores, qinichelins, from Streptomyces sp. MBT76, revealing their biosynthesis involves multiple gene clusters.