This study shows that polysomes and mRNA organization control cytoplasmic biophysical properties by affecting diffusivity through translation inhibition and mRNA condensation.

Cell Reports · Sep 1, 2025Peer-reviewedCell Biology

The scramblases VMP1 and TMEM41b are required for primitive endoderm specification by targeting WNT signaling

Markus Holzner, Tea Sonicki, Hugo Hunn, Federico Uliana, Weijun Jiang, Vamshidhar R. Gade, Karsten Weis, Anton Wutz, Giulio Di Minin

This study shows that VMP1 and TMEM41b are required for primitive endoderm specification by regulating WNT signaling in mouse ESCs.

Cell Death and Differentiation · Dec 18, 2024Peer-reviewedDevelopmental Biology

A novel nematode species from the Siberian permafrost shares adaptive mechanisms for cryptobiotic survival with C. elegans dauer larva

Anastasia V. Shatilovich, Vamshidhar R. Gade, Martin Pippel, Tarja T. Hoffmeyer, Alexei V. Tchesunov, Lewis Stevens, Sylke Winkler, Graham M. Hughes, Sofia Traikov, Michael Hiller, Elizaveta Rivkina, Philipp H. Schiffer, Eugene Wimberly Myers, Teymuras V. Kurzchalia

The paper identifies a new nematode species from Siberian permafrost and shows it shares cryptobiosis mechanisms with C. elegans dauer larvae.

bioRxiv · Jan 28, 2022 · PreprintGenomics