Author

Erik McShane

Harvard UniversityORCID 0000-0002-7806-2063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. Stirling ChurchmaniD· 3 shared Autum R. Baxter‐KoenigsiD· 2 shared Albert XuiD· 1 shared Barbara TreutleiniD· 1 shared Becky Xu Hua FuiD· 1 shared Brendan M. Smalec· 1 shared Caroline A M WeissiD· 1 shared Chantal K. GuegleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

L. Stirling ChurchmanORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 28, 2026

Analog intrinsic recoding measures RNA dynamics without chemical conversion

Lisa N. Hansen, Mary Couvillion, Erik McShane…·L. Stirling Churchman

The paper introduces AIR-seq, a method that measures RNA dynamics without chemical conversion, improving RNA velocity inference and revealing hidden regulation.

DOI 10.64898/2026.07.27.741041

bulk RNA-seqscRNA-seq

𝕏 PostBluesky

Cell BiologyLife Science AlliancePeer-reviewedJun 16, 2025

Transcription arrest induces formation of protective RNA granules in mitochondria

Katja G. Hansen, Autum R. Baxter‐Koenigs, Caroline A M Weiss…·L. Stirling Churchman

The paper shows that transcription arrest in mitochondria leads to the formation of RNA granules that protect mt-mRNAs and help restore OXPHOS balance.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsMolecular CellPeer-reviewedJul 1, 2024

Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle

Robert Ietswaart, Brendan M. Smalec, Albert Xu…·L. Stirling Churchman

The paper quantifies RNA flow across subcellular compartments using TimeLapse-seq and identifies factors influencing mRNA life cycles.

82 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky