Author

Diana Wing Lee

Moderna Therapeutics (United States)ORCID 0000-0002-7861-3128Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniela Montes Berrueta· 4 shared Tessa SpeideliD· 4 shared Andrea Carfı́iD· 3 shared Arshan NasiriD· 3 shared Darin K. EdwardsiD· 3 shared Yadunanda BudigiiD· 3 shared Amy Gorrie· 2 shared Hardik JaniiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Daniela Montes Berrueta

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4 papers

Recent·Most cited

ImmunologyJournal of VirologyPeer-reviewedApr 27, 2026

Predictive Modeling of Immune Escape and Antigenic Grouping of SARS-CoV-2 Variants

Arshan Nasir, Diana Wing Lee, Laura E. Avena…·Darin K. Edwards

The paper develops a risk calculator to predict immune escape of SARS-CoV-2 variants and group antigenically related variants to guide vaccine strain selection.

5 citationstop 1%

virusbulk RNA-seq

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ImmunologybioRxivPreprintSep 16, 2025

mRNA-1273.251 and mRNA-1283.251 vaccines expressing SARS-CoV-2 variant LP.8.1 antigens broadly neutralize contemporary JN.1-lineage viruses

Arshan Nasir, Diana Wing Lee, Ziqiu Wang…·Alec W. Freyn

This study develops and evaluates two mRNA vaccines targeting the LP.8.1 variant of SARS-CoV-2, showing broad neutralization against JN.1-lineage subvariants.

1 citation

mouseexperimental assay

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ImmunologyNature MicrobiologyPeer-reviewedJun 10, 2025

Viral evolution prediction identifies broadly neutralizing antibodies against existing and prospective SARS-CoV-2 variants

Fanchong Jian, Anna Z. Wec, Leilei Feng…·Yunlong Cao

This paper predicts SARS-CoV-2 RBD evolution using deep mutational scanning to identify broadly neutralizing antibodies effective against existing and prospective variants.

57 citationstop 1%

humanproteomics

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ImmunologyVaccinePeer-reviewedMar 7, 2025

mRNA-1273 vaccines adapted to JN.1 or KP.2 elicit cross-neutralizing responses against the JN.1 sublineages of SARS-CoV-2 in mice

Diana Wing Lee, Arshan Nasir, Sayda M. Elbashir…·Yadunanda Budigi

This study evaluates JN.1 and KP.2 mRNA vaccines in mice, showing they elicit strong neutralizing antibodies against JN.1 subvariants and cross-neutralize KP.3, LA.2, and XEC.

16 citationstop 1%

mouseexperimental assay

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