Author

Daniela Montes Berrueta

Moderna Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Diana Wing LeeiD· 4 shared Tessa SpeideliD· 4 shared Andrea Carfı́iD· 3 shared Arshan NasiriD· 3 shared Darin K. EdwardsiD· 3 shared Yadunanda BudigiiD· 3 shared Amy Gorrie· 2 shared Hardik JaniiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Diana Wing LeeORCID

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Author profile →

4 papers

Recent·Most cited

Predictive Modeling of Immune Escape and Antigenic Grouping of SARS-CoV-2 Variants

Arshan Nasir, Diana Wing Lee, Laura E. Avena, Daniela Montes Berrueta, Tessa Speidel, Kai Wu, Yadunanda Budigi, Andrea Carfı́, Guillaume B. E. Stewart-Jones, Darin K. Edwards

The paper develops a risk calculator to predict immune escape of SARS-CoV-2 variants and group antigenically related variants to guide vaccine strain selection.

Journal of Virology · Apr 27, 2026Peer-reviewedImmunology

mRNA-1273.251 and mRNA-1283.251 vaccines expressing SARS-CoV-2 variant LP.8.1 antigens broadly neutralize contemporary JN.1-lineage viruses

Arshan Nasir, Diana Wing Lee, Ziqiu Wang, Clinton O. Ogega, Nathen E. Bopp, Phylicia Wisti, Daniel L. Makrinos, Hardik Jani, Amy Gorrie, Michael F. Bender, Adrian R. Laciak, Arvind Sharma, Xiaozhen Hu, Tessa Speidel, Fadi Ghantous, , Alec W. Freyn

This study develops and evaluates two mRNA vaccines targeting the LP.8.1 variant of SARS-CoV-2, showing broad neutralization against JN.1-lineage subvariants.

bioRxiv · Sep 16, 2025 · PreprintImmunology

Viral evolution prediction identifies broadly neutralizing antibodies against existing and prospective SARS-CoV-2 variants

Fanchong Jian, Anna Z. Wec, Leilei Feng, Yuanling Yu, Lei Wang, Peng Wang, Lingling Yu, Jing Wang, Jacob Hou, Daniela Montes Berrueta, Diana Wing Lee, Tessa Speidel, LingZhi Ma, Thu Kim, Ayijiang Yisimayi, , Yunlong Cao

This paper predicts SARS-CoV-2 RBD evolution using deep mutational scanning to identify broadly neutralizing antibodies effective against existing and prospective variants.

Nature Microbiology · Jun 10, 2025Peer-reviewedImmunology

mRNA-1273 vaccines adapted to JN.1 or KP.2 elicit cross-neutralizing responses against the JN.1 sublineages of SARS-CoV-2 in mice

Diana Wing Lee, Arshan Nasir, Sayda M. Elbashir, Hardik Jani, Tessa Speidel, Amy Gorrie, Daniela Montes Berrueta, Philippa Martin, Swan Tan, Yixuan Jacob Hou, Kath Hardcastle, Darin K. Edwards, Kai Wu, Andrea Carfı́, Yadunanda Budigi

This study evaluates JN.1 and KP.2 mRNA vaccines in mice, showing they elicit strong neutralizing antibodies against JN.1 subvariants and cross-neutralize KP.3, LA.2, and XEC.

Vaccine · Mar 7, 2025Peer-reviewedImmunology