Author

Komal Srivastava

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:CITE-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Florian KrammeriD· 3 shared Viviana R. SimoniD· 3 shared Bailey Bozarth· 2 shared Camila H. CoelhoiD· 2 shared Gagandeep SinghiD· 2 shared Giulio KleineriD· 2 shared Goran BajiciD· 2 shared Hallie CohniD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Florian KrammerORCID

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4 papers

Recent·Most cited

The buried S2 apex of SARS-CoV-2 spike elicits an immunodominant germline-restricted public antibody response

Suncheol Park, Jacob Mischka, Nisreen M.A. Okba, Anass Abbad, Meng Yuan, Komal Srivastava, Charles Gleason, Lubbertus C. F. Mulder, Jeffrey Copps, Katrina Saam, Sandhya Bangaru, Florian Krammer, Ian A. Wilson, Viviana R. Simon, Andrew B. Ward

This study identifies an immunodominant S2 apex epitope in SARS-CoV-2 that elicits a public antibody clonotype, highlighting its role as a barrier to universal coronavirus vaccines.

bioRxiv · Feb 19, 2026 · PreprintImmunology

T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome.

Cansu Cimen Bozkus, Matthew Brown, Leandra G. Velazquez, Marcus Thomas, Eric A. Wilson, Timothy J. O’Donnell, Anna Kaminska, Denis Ruchnewitz, Douglas Geertz, Yonina Bykov, Julia Kodysh, Kasopefoluwa Y. Oguntuyo, Vladimir Roudko, David Hoyos, Komal Srivastava, , Nina Bhardwaj

The paper maps T cell epitopes in SARS-CoV-2, showing that immunodominant regions are conserved across variants and important for immune surveillance.

iScience · Jul 2, 2025Peer-reviewedImmunology

Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines

Raianna Farhat Fantin, Jordan J. Clark, Hallie Cohn, Deepika Jaiswal, Bailey Bozarth, Vishal Rao, Alesandro Civljak, Igor Lobo, Jessica Nardulli, Komal Srivastava, Jeremy S. Yong, Robert Andreata‐Santos, Kaitlyn Bushfield, Edward S. Lee, Gagandeep Singh, , Camila H. Coelho

This study evaluates monoclonal antibody responses to XBB.1.5 vaccines by analyzing plasmablasts from vaccinated individuals and characterizing their binding and neutralization properties against SARS-CoV-2 variants.

The Lancet Microbe · May 30, 2025Peer-reviewedImmunology

Convergent and clonotype-enriched mutations in the light chain drive affinity maturation of a public antibody

Vishal Rao, Iden A. Sapse, Hallie Cohn, Duck-Kyun Yoo, Pei Tong, Jordan Clark, Bailey Bozarth, Yuexing Chen, Komal Srivastava, Gagandeep Singh, Florian Krammer, Viviana R. Simon, Duane R. Wesemann, Goran Bajic, Camila H. Coelho

The paper identifies clonotype-enriched mutations in the light chain of a public antibody that enhance affinity for a conserved viral epitope and increase after repeated vaccinations.

bioRxiv · Mar 7, 2025 · PreprintImmunology