Lifeng Xu

Telomere variant sequences encode the genetic blueprint for allele-specific telomere length

The paper identifies heritable telomere variant sequences that determine allele-specific telomere length and shows their role in telomere maintenance and inheritance.

Host Microenvironment Reprogramming by Saccharides Overcomes Lung Barriers for mRNA Therapeutics

This paper identifies glucose as a reprogramming agent for the airway microenvironment to enhance mRNA delivery and efficacy in lung models.

Bmmp influences wing shape by regulating anterior-posterior and proximal-distal axis development

This study identifies Bmmp as a gene regulating wing shape in silkworms and Drosophila by modulating axis development, revealing its functional conservation and potential for pest control.

The structurally conserved TELR region on shelterin protein TPP1 is essential for telomerase processivity but not recruitment

This study identifies TPP1 mutations that impair telomerase processivity without affecting recruitment, showing processivity is critical for telomere length homeostasis.