In situ molecular architecture of PML bodies reveals open-state columnar trinucleosome assemblies within a porous, chromatin-permissive interior
Vojtěch Pražák, Iain Harley, Julian Falckenhayn, Chris Boutell, Peter A. Thomason, Benjamin G. Davis, Rainer Kaufmann, Stephen D. Carter
This study uses cryo-CLEM to reveal the molecular structure of PML bodies, identifying columnar trinucleosome assemblies and a porous interior that may facilitate chromatin partitioning.
bioRxiv · Jun 10, 2026 · PreprintCell Biology